New medication by Roche to relief the burden of the disease & stop its progression
International and regional medical experts meeting in Dubai this week addressed the importance of early detection and adequate treatment for patients afflicted by rheumatoid arthritis (RA), an auto-immune disease resulting in the loss of joint function which often leads to disability and other systemic complications. The event was organized by Roche, the worldâ€™s largest biotech company, where it announced the launch of its innovative drug, ActemraÂ® (tocilizumab), the only product to show superiority over methotrexate (MTX), the most widely used treatment against rheumatoid arthritis.
Research has shown that rheumatoid arthritis patients have high levels of interleukin-6 (IL-6), the key cytokine or protein involved in the inflammatory process. The overproduction of IL-6 leads to inflammation, swelling, joint damage and destruction, as well as other symptoms. Speaking at the event, Business Unit Director, Roche UAE,Dr. Hesham El-Bakr, said: â€œBy blocking the action of IL-6, Actemra, the worldâ€™s first IL-6 receptor-inhibiting monoclonal antibody, rapidly improves the signs and symptoms by reducing inflammation both in the joints and throughout the body, thereby helping more RA patients to achieve the ultimate goal of remission.â€
Rheumatoid arthritis is generally diagnosed through several symptoms and signs such as morning stiffness for an hour, pain and swelling of joints, and general weakness. The experts called on patients who notice these and other signs and symptoms to seek a rheumatologistâ€™s opinion.
Over a hundred specialists from around the world participated in the one-day medical convention. Medical experts including Ernest Choy from the UK, Jean Dudler from Switzerland, Andrea Rubbert from Germany, Adel Al Awadhi from Kuwait, Mohamed Hamoudeh from Qatar and others addressed the latest clinical trials and case studies linked to Actemra. Rheumatologists also underlined the importance of optimization of the treatment options in Rheumatoid Arthritis and called on patients to seek early specialist opinion.
â€œThe key thing here is early detection in order to determine the best course for treatment which ideally should help doctors treat the symptoms and stop progression of the disease. â€œWe look forward to using this new treatment option which will help our patients better manage RA signs and symptoms and hopefully substantially modify the course of the diseaseâ€ said Dr. Waleed Al Shehhi, consultant rheumatologist and president of the Emirates Society Rheumatology (ESR) in the UAE.
Dr. Mohamad Al Marzouqi, consultant rheumatologist at Sheikh Khalifa Medical Centre (SKMC), who participated in the convention said: â€œthe latest clinical trials and case studies that were presented by colleagues from all over the world, showed that Actemra delivers a unique combination of a rapid onset of action and an efficacy that keeps improving over time. This means that many of my patients have now a new hope that will help them deal with this life-changing disease that affects them both physically and emotionallyâ€.
According to the World Health Organisationâ€™s latest statistics about 1% of the worldâ€™s population suffers from rheumatoid arthritis. Twice as many women are generally affected by RA than men. The earlier the disease starts, the more likely it is that patients will become severely disabled. The disease also impacts the average life expectancy, shortening it by three to seven years.1
- WHO, Global burden and incidence of rheumatoid arthritis, 2000
Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the worldâ€™s largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and central nervous system (CNS). Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Rocheâ€™s personalised healthcare strategy aims at providing medicines and diagnostic tools that enable tangible improvements in the health, quality of life and survival of patients.